| 1.1 |
Statement from the Chairman of the Executive Board or Supervisory Board (CR-Report* p.2/3) |
| 1.2 | Description of key impacts, risks and opportunities (CR-Report* p.7, 11, 14, 17-20, 23-26, 32-32, 37-38, 42) |

| 2.1 | Name of the organization |
| 2.2 | Primary brands, products, and/or services (CR-Report* p.8-9, 17-20, 23-26, 42, 54-55) |
| 2.3 | Operational structure of the organization
(CR-Report* p.7-9, 50, 54-55) |
| 2.4 | Location of organization’s headquarters (CR-Report* p.8, Imprint) |
| 2.5 | Number / name of countries with either major operations (CR-Report* p.7-8, 29, 35, 51) |
| 2.6 | Nature of ownership and legal form (CR-Report* p.7, 53, GB 28-29, GB 65-67) |
| 2.7 | Markets served
(CR-Report* p.7-8, 51) |
| 2.8 | Scale of the reporting organization (CR-Report* p.6-9, 29, 50-52, 57) |
| 2.9 | Significant changes during the reporting period regarding size, structure, or ownership
(CR-Report* p.8, 17, 21, 33, 53) |
| 2.10 | Awards received in the reporting period
(CR-Report* p.21, 27, 29, 30, 33, 37, 61, 68-69) |

| Report profile | |
| 3.1 | Reporting period: business years 2007 and 2008, partially until June 2009 |
| 3.2 | Date of most recent previous report: 11/2007 |
| 3.3 | Reporting cycle: CR-Report every 2 years, Facts and figures yearly |
| 3.4 | Contact point for questions regarding the report or its contents Maria Schaad, Tel. (06151) 72-0, E-Mail: corpcom@merck.de |
| Report scope and boundary | |
| 3.5 | Process for defining report content (incl. priorities) (CR-Report* „About this Report“) |
| 3.6 | Boundary of the report (CR-Report* „About this Report“) |
| 3.7 | Specific limitations on the scope or boundary of the report (CR-Report* „About this Report“)) |
| 3.8 | Basis for reporting on joint ventures, etc (CR-Report* „About this Report“) |
| 3.9 | Data measurement techniques and the bases for calculation (CR-Report* p.37, 57, 60, 62, 65) |
| 3.10 | Explanation of the effect of any re-statements of information provided in earlier reports (CR-Report* p.50-51, 57, 60, 62-63) |
| 3.11 | Significant changes from previous reporting periods in the scope, boundary, or measurement methods applied in the report (CR-Report* p.37, 50, 57, 60, 62, 64) |
| 3.12 | GRi content index – Table identifying the location of standard disclosures in the report (CR-Report* p.71) |
| 3.13 | External verficiation of this report |

| Governance | |
| 4.1 | Governance structure of the organization, incl. responsibility for sustainability: Company management
Factsheet “Company management and stakeholders” (CR-Report* p.7, 14-15) |
| 4.2 | Chairman
Factsheet “Company management and stakeholders” (CR-Report* p.14, GB 68-69) |
| 4.3 | Governance structure Company management
Factsheet “Company management and stakeholders” (GB 65-69) |
| 4.4 | Mechanisms for shareholders and employees to provide
recommendations or direction to the highest governance body ** |
| 4.5 | Linkage between compensation for members of senior executives and the organization’s sustainability performance **
Corporate Governance Factsheet “Company management and stakeholders” (GB 67) |
| 4.6 | Processes in place to ensure conflicts of interest are avoided
Factsheet “Company management and stakeholders” (CR-Report* p.13) |
| 4.7 | Expertise of the governance bodies with respect to sustainability
Factsheet “Company management and stakeholders” (CR-Report* p.14) |
| 4.8 | Mission statement, company values and Code of Conduct
(CR-Report* p.1, 11-15) |
| 4.9 | Executive / Supervisory Board level for overseeing economic, environmental and social risks and opportunities
Factsheet “Company management and stakeholders” (CR-Report* p.14-15, GB 61-64) |
| 4.10 | Processes for evaluating the Exeucutive Board’s own performance Factsheet
Factsheet “Company management and stakeholders” (CR-Report* p.14-15) |
| Commitment to external initiatives | |
| 4.11 | Application of the precautionary principle
Sustainability program Factsheets “Pharmaceutical Products” and “Chemical Products” (CR-Report* p.6, 7, 11-15, 19-21, 23, 25, 26, 29, 37, 42, 56, 57-58) |
| 4.12 | Initiativen External initiatives that the organization endorses
Factsheet “Company management and stakeholders” (CR-Report* p.13, 18-19, 20, 24, 25, 26, 36, 38, 41-42, 69, 70) |
| 4.13 | Principle memberships in industry and business associations
stakeholder engagement Factsheet “Company management and stakeholders” (CR-Report* p.13, 19, 36) |
| Stakeholder engagement | |
| 4.14 | List of stakeholder groups engaged by the organization
Factsheet “Company management and stakeholders” (CR-Report* p.68-69) |
| 4.15 | Basis for identification and selection of stakeholders with whom to engage
Factsheet “Company management and stakeholders” (CR-Report* p.15, 36, 39) |
| 4.16 | Approaches to stakeholder dialogue (frequency/type)
Factsheet “Company management and stakeholders” (CR-Report* p.11, 13, 18, 19, 20, 26, 29-30, 36, 39, 43, 53, 68-69) |
| 4.17 | Organization’s response to key topics and concerns that have been raised through stakeholder engagement
Factsheet “Company management and stakeholders” (CR-Report* p.15, 20, 30, 33, 39, 68-69) |

| Economic | ||
| Management approach
Economic figures (CR-Report* p. 11-15) |
||
| aspect : economic performance | ||
| EC1 | Direct economic value generated and distributed
Facts & Figures Economic figures (CR-Report* p.6-7, 50-53, 67) |
|
| EC2 | Financial implications of climate change
Economic figures (CR-Report* p.37**) (Information against the Carbon Disclosure Project - extern link) http://www.cdproject.net |
|
| EC3 | Coverage of the organization’s defined benefit plan obligations
Social benefits Economic figures (CR-Report* p.33, 52-53, 58-62) |
|
| EC4 | Significant financial assistance received from government
(CR-Report* p.18**, 24**, 25**, GB 106) |
|
| aspect: market presence | ||
| EC6 | Spending on local suppliers
(CR-Report* p.51) |
|
| EC7 | Employment of local staff in senior management positions
(CR-Report* p.30-32**, 60**) |
|
| aspect: indirect economic impacts | ||
| EC8 | Infrastructure investments and services provided primarily for public benefit
Responsibility for the community Economic figures (CR-Report* p.19, 20, 42-43, 47, 53, 66-67) |
|

| Environmental | |
| Management approach:
Environment and Safety EHS Management Environment (CR-Report* p.35-39, 47, 62) |
|
| aspect: materials | |
| EN1 | Materials used by weight or volume
(CR-Report* p.62**, 64**) |
| EN2 | Percentage of materials used that are recycled input materials
Environment (CR-Report* p.47, 65**) |
| aspect: energy | |
| EN3 | Direct energy consumption by primary energy source
Environment (CR-Report* p.62) |
| EN4 | Indirect energy consumption by primary source
Environment (CR-Report* p.63) |
| aspect: water | |
| EN8 | Total water withdrawal by source
Environment (CR-Report* p.64) |
| aspect: biodiversity | |
| EN11 | Use of land in protected areas
Environment (CR-Report* p.39, 65) |
| EN12 | Impact of activities in protected areas
Environment (CR-Report* p.39, 65) |
| aspect: emissions, effluent and waste | |
| EN16 | Total direct and indirect greenhouse gas emissions
Environment (CR-Report* p.37-38, 47, 63) |
| EN17 | Other relevant indirect greenhouse gas emissions caused by business travel and employee commuting Environment
(CR-Report* p.65**) |
| EN19 | Emissions of ozone-depleting substances by weight |
| EN20 | NO, SO, and other significant air emissions by weight
Environment (CR-Report* p.63) |
| EN21 | Total water discharge by quality and destination
Environment (CR-Report* p.64) |
| EN22 | Total weight of waste by type and disposal method
Environment (CR-Report* p.65) |
| EN23 | number and volume of significant spills |
| aspect: products and services | |
| EN26 | Initiatives to mitigate environmental impacts of products and services
Preclinic Regulatory Support Chemicals Factsheets “Pharmaceutical Products” and “Chemical Products” (CR-Report* p.23-25, 26, 27, 36, 46, 55) |
| EN27 | Percentage of products sold and their packaging materials that are reclaimed by category Merck-Disposal-Service
Chemicals Environment |
| aspect: compliance | |
| EN28 | Significant fines/ Fines for non-compliance with environmental laws - none |

| Social | |
| Working environment and working | |
| Management approach:
Employees Health and safety Employees and Human Rights (CR-Report* p.11, 13, 29-33, 46-47, 57-62) |
|
| aspect: employment | |
| LA1 | Total workforce by employment contract, and region
Employees and Human Rights (CR-Report* p.7, 57-58) |
| LA2 | Total number and rate of employee turnover by age group, gender, and region aspect: labor
management relations Employees and Human Rights (CR-Report* p.61**) |
| aspect: codetermination | |
| LA4 | Percentage of employees covered by collective bargaining agreements Employees and Human Rights (CR-Report* p.58) |
| LA5 | Minimum notice period(s) regarding operational changes
(CR Report* p.32**) |
| aspect: occupational health and safety | |
| LA7 | Injuries, absenteeism, fatalities
Employees and Human Rights (CR-Report* p.47, 58-59) |
| LA8 | Risk control programs in place regarding serious diseases
Employees and Human Rights (CR-Report* p.59) |
| aspect: training and education | |
| LA10 | Average hours of training by employee category
Personnel development (CR Report* p.11, 13, 32, 36, 46, 61) |
| aspect: dversity and equal opportunity | |
| LA13 | Composition of executive management (e.g. gender/nationality)
Equal opportunity (CR Report* p.32**, 46, 60) |
| LA14 | Compensation by gender and employee category
Employees and Human Rights (CR Report* p.60) |

| Human rights | |
| Management approach:
Employees and Human Rights (CR-Report* p.13, 46, 66) |
|
| aspect: investment and procurement practices | |
| HR1 | Investment agreements that include human rights clauses
or that have undergone human rights screening Employees and Human Rights (CR-Report* p.13, 46, 66) |
| HR2 | Percentage of significant suppliers and contractors that have undergone screening on human rights and actions taken
Employees and Human Rights (CR-Report* p.13, 46, 66) |
| aspect: non-discrimination | |
| HR4 | Total number of incidents of discrimination and actions taken
Equal opportunity Employees and Human Rights |
| aspect: Freedom of association and collective bargaining | |
| HR5 | Operations with significant risk
Employees and Human Rights (CR-Report* p.58) |
| aspect: child labor | |
| HR6 | Operations identified as having significant risk and measures taken
Employees and Human Rights (CR-Report* p.13, 51, 58) |
| aspect: Forced and compulsory labor | |
| HR7 | Operations identified as having significant risk and measures taken
Employees and Human Rights (CR-Report* p.13, 51) |
| Society | |
| Management approach:
Community Economic figures (CR-Report* p.11, 13, 15, 41) |
|
| aspect: community | |
| SO1 | Mitigation of negative impacts of operations on local communities
Economic figures (CR-Report* p.15, 32-33, 39, 66-67) |
| aspect: corruption | |
| SO2 | Percentage and total number of business units analyzed for risks
Economic figures (CR-Report* p.66) |
| SO3 | Percentage of employees trained in anti-corruption policies and procedures
Economic figures (CR-Report* p.13, 66**) |
| SO4 | Actions taken in response to incidents of corruption: no cases of corruption Economic figures
(CR-Report* p.66) |
| aspect: public policy | |
| SO5 | Public policy positions and participation in public policy
(CR-Report* p.12-13, 15, 26, 36) |
| aspect: compliance | |
| SO8 | Significant fines / sanctions for violation of laws - none |
| Product responsibility | |
| Management approach:
Factsheets “Pharmaceutical Products” and “Chemical Products” (CR-Report* p.11, 17, 23, 26) |
|
| aspect: customer health and safety | |
| PR1 | Life cycle stages in which health and safety impacts of products and services are assessed for improvement:
Pharmaceutical products Clinical Trials Chemical products Factsheets “Pharmaceutical Products” and “Chemical Products” (CR-Report* p.18-20, 26, 55) |
| aspect: products and services | |
| PR3 | Principles / methods of product information and labeling
Chemical products REACH Factsheets “Pharmaceutical Products” and “Chemical Products” (CR-Report* p.19, 20, 26, 46, 55) |
| aspect: marketing communication | |
| PR6 | Programs for adherence to laws and voluntary codes related to marketing
Responsible advertising Chemical products Factsheets “Pharmaceutical Products” and “Chemical Products” (CR-Report* p.20) |
| aspect: compliance | |
| PR9 | Monetary fines for violations of laws concerning the provision and use of products and services - none |
